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After losing his wife seven years earlier, the eccentric Dr. John Dolittle, famed doctor and veterinarian of Queen Victoria’s England, hermits himself away behind the high walls of Dolittle Manor with only his menagerie of exotic animals for company. But when the young queen falls gravely ill, a reluctant Dolittle is forced to set sail on an epic adventure to a mythical island in search of a cure, regaining his wit and courage as he crosses old adversaries and discovers wondrous creatures. The doctor is joined on his quest by a young, self-appointed apprentice and a raucous coterie of animal friends, including an anxious gorilla, an enthusiastic but bird-brained duck, a bickering duo of a cynical ostrich and an upbeat polar bear and a headstrong parrot, who serves as Dolittle’s most trusted advisor and confidante.

Starring Robert Downey Jr., Antonio Banderas, Michael Sheen, Jim Broadbent and Harry Collett, as well as featuring the voices of John Cena, Marion Cotillard, Carmen Ejogo, Ralph Fiennes, Selena Gomez, Tom Holland, Rami Malek, Kumail Nanjiani, Craig Robinson, Octavia Spencer, Emma Thompson and Frances de la Tour, the film is released Januaty 17 in the U.S. and the UK.